Long-term effects of childhood cancer treatment on hormonal and ultrasound markers of ovarian reserve

This study demonstrated that the majority of CCSs do not show signs of a reduced ovarian reserve. However, specific subgroups of CCSs appear to be associated with a high risk. Our results are important for counselling CCSs and future patients regarding parenthood and fertility preservation.STUDY FUNDING/COMPETING INTERESTSThis study was funded by the Dutch Cancer Society (Grant no. VU 2006-3622) and by the Children Cancer Free Foundation (Project no. 20). Philips Health Systems Benelux supported this study by providing three ultrasound systems and concomitant analytic software. There are no competing interests.TRIAL REGISTRATION NUMBERNTR2922 http://www.trialregister.nl/trialreg/admin/rctview.asp?TC = 2922
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research