How Pregnancy May Affect the Risk of Alzheimer ’s

In the U.S., two-thirds of people with Alzheimer’s disease are women, according to the Alzheimer’s Association. For decades, experts have explained the gender divide by the fact that women also tend to live longer than men, and the biggest risk factor for Alzheimer’s is age. “Everyone brushed it off to the fact that women were living longer,” says Rachel Whitmer, professor of epidemiology at University of California Davis. “Now science is saying, wait, that’s not the end of the story.” Pregnancy, according to two of the latest studies on the issue, may have something to do with it. The new studies come to opposite conclusions about pregnancy and the risk of dementia. One study found that the more children a woman had, the lower her risk of developing dementia, while another found that having five or more children was tied to a higher risk of Alzheimer’s. Both studies—though their findings conflict—point to the need for more studies investigating the under-researched area. Whitmer and her colleague Paola Gilsanz, a staff scientist from the Kaiser Permanente Division of Research, presented data on their study at the annual meeting of the Alzheimer’s Association. They analyzed health information from more than 14,500 women who were members of Kaiser Permanente from the 1960s to 2017. They tracked the women’s reproductive milestones, including their first period, the number of children and miscarriages...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Brain healthytime Source Type: news

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Authors: Mitolo M, Tonon C, La Morgia C, Testa C, Carelli V, Lodi R Abstract BACKGROUND: Bright light treatment is a therapeutic intervention mainly used to treat sleep and circadian disturbances in Alzheimer's disease (AD) patients. Recently, a handful of studies also focused on the effect on cognition and behavior. Conflicting findings are reported in the literature, and no definite conclusions have been drawn about its specific therapeutic effect. SUMMARY: The aim of this review is to provide a critical evaluation of available evidence in this field, highlighting the specific characteristics of effective bri...
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
CONCLUSIONS: The VRTC exercise posed a protective effect for some cognitive and physical functions in older adults with CI. The more engaging the program, the greater the improvement in the cognitive performance. PMID: 30537752 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
CONCLUSION: Individuals with AD are at higher risk of manifesting aggressive behaviors than healthy individuals or those with MCI. Our findings not only underscore the necessity of treatment of aggressive behaviors in AD but also highlight the importance of preventing the transition from MCI to AD. PMID: 30527275 [PubMed - as supplied by publisher]
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research
Role of the mTOR‑FOXO1 pathway in obesity‑associated renal tubulointerstitial inflammation. Mol Med Rep. 2018 Dec 05;: Authors: Sun H, Shao X, He J, Golos M, Shi B Abstract Since obesity is largely responsible for the growing incidence of renal tubulointerstitial inflammation, exploration into the mechanisms of obesity‑associated tubulointerstitial inflammation is essential. Studies have demonstrated that mammalian target of rapamycin (mTOR) is a crucial molecule in the pathogenesis of renal inflammation, including regulating the expression of inflammatory factors. The purpose of the present...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
DISCUSSION: Dietary changes initiated during the intervention were related to changes in executive function in 2 years. Long-term diet appeared more influential for global cognition. PMID: 30527596 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
Background: Elevated HIV viral load (VL) in pregnancy has been linked to increased risk of mortality, immunologic abnormalities, infectious morbidity and restricted growth among HIV-exposed uninfected (HEU) children, but little is known about effects on child development. Methods: HIV-infected women initiating lifelong antiretroviral therapy (ART; tenofovir + emtricitabine + efavirenz) antenatally were followed from first antenatal visit through delivery and with their breastfed infants postpartum. Cognitive, motor and expressive language development (Bayley Scales of Infant and Toddler Development-Third Edition; delay defined as score
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: HIV Reports Source Type: research
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
Source: Journal of Pediatric Endocrinology and Metabolism - Category: Endocrinology Source Type: research
By Christian Jarrett “Learning styles” – there can be few ideas that have created such a stark disconnect between the experts on the ground and the evidence published in scholarly journals. Endorsed by the overwhelming majority of teachers, yet dismissed by most psychologists and educational neuroscientists as a “neuromyth”, the basis of learning styles is that people learn better when taught via their preferred learning modality, usually (but not always) described as either visual, auditory or kinaesthetic. Many studies have already uncovered serious problems with the learning styles concept,...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Educational Source Type: blogs
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Source: The Guttmacher Institute - Category: International Medicine & Public Health Authors: Source Type: news
The national health impact could be substantial, preventing more than 190,000 cases of diabetes and 16,000 cases of cancerWe don ’t often equate the kilojoules we drink in our glass of wine or pint of beer with the weight that accumulates around our middle. Butour new study shows increasing the price of alcohol is the foremost value-for-money policy option to prevent obesity in Australia.The study, released today, shows if we increase alcohol taxes by standardising them across different types of alcohol, overall alcohol consumption would go down. This would lead to substantial reductions in the kilojoules Australians...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Health Alcohol Tax Obesity Australia news Business (Australia) Medical research Source Type: news
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