Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.

In conclusion, Rg1 produced hepatoprotective effects against APAP-induced acute liver injury via Nrf2 signaling pathway. Rg1 might be an effective approach for the prevention against acute liver injury.
PMID: 30030101 [PubMed - as supplied by publisher]

Source: Regulatory Toxicology and Pharmacology : RTP - July 17, 2018 Category: Toxicology Authors: Ning C, Gao X, Wang C, Kong Y, Liu Z, Sun H, Sun P, Huo X, Ma X, Meng Q, Liu K Tags: Regul Toxicol Pharmacol Source Type: research