Impact of the 719Arg variant of KIF6 and major cardiovascular events on patients who received statins: a systematic review and meta-analysis.

Conclusions Statin therapy significantly reduced the risk for MACEs in subjects carrier specific KIF6 gene Trp719Arg polymorphisms. Further, subjects carrying ArgTrp or ArgArg+ArgTrp had a greater incidence of MACEs as compared with TrpTrp when they received statins.
PMID: 29938614 [PubMed - as supplied by publisher]

Source: Current Pharmaceutical Design - June 24, 2018 Category: Drugs & Pharmacology Authors: Chen S, Xiang Q, Zhao X, Xie Q, Zhou S, Zhang Z, Mu G, Cui Y Tags: Curr Pharm Des Source Type: research