Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System

Conditions:   Untreated Childhood Medulloblastoma;   Untreated Childhood Supratentorial Primitive Neuroectodermal TumorInterventions:   Drug: vorinostat;   Drug: isotretinoin;   Drug: vincristine sulfate;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: thiotepa;   Procedure: peripheral blood stem cell transplantation;   Radiation: 3-dimensional conformal radiation therapy;   Other: laboratory biomarker analysisSponsor:   National Cancer Institute (NCI)Recruiting - verified June 2014
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials