Immunohistochemical study on neuropilin 1 (NRP1) immunoexpression in oral squamous cell carcinoma.

CONCLUSIONS: The present study revealed overexpression of NRP1 in OSCC, especially in OSCC patients with metastasis, suggesting that NRP1 could potentially contribute to metastasis of oral cancer. The correlation between the number of NRP1+ infiltrating cells and CD163+ macrophages suggests that NRP1+ infiltrating macrophages are present in tumor microenvironment and may play a role in the progressions of oral cancer. PMID: 29873058 [PubMed - as supplied by publisher]
Source: Folia Histochemica et Cytobiologica - Category: Cytology Tags: Folia Histochem Cytobiol Source Type: research