High fat diet induced obesity is mitigated in Cyp3a-null female mice.

In conclusion, lack of Cyp3a has a positive effect on acclimation to a HFD in females as it improves weight gain, glucose response and ketosis.
PMID: 29738703 [PubMed - indexed for MEDLINE]

Source: Chemico-Biological Interactions - June 1, 2018 Category: Molecular Biology Authors: Kumar R, Litoff EJ, Boswell WT, Baldwin WS Tags: Chem Biol Interact Source Type: research