Phenobarbital monotherapy for alcohol withdrawal syndrome in the non-intensive care unit setting: a review

ConclusionsThe availability of literature evaluating phenobarbital was limited. Phenobarbital regimens varied between cases and studies and, although generalizations regarding phenobarbital use for treatment or prevention of AWS cannot be made, phenobarbital has demonstrated tolerability in limited cases. A benefit-to-risk assessment should be conducted prior to using phenobarbital. Providers should consider clinical evidence in addition to phenobarbital clinical pharmacology in product selection.
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research