Log in to search using one of your social media accounts:

 

C.O. Truxton, Inc. Issues Voluntary Nationwide Recall of Amitriptyline HCL Tablets, USP 50mg and Phenobarbital Tablets, USP 15mg, 30mg, 60mg, 100mg Due to Potential Label Mix-Up
Bellmawr, New Jersey, C.O. Truxton, Inc. is expanding their 04/21/2017 voluntary recall, as a precaution to include the following C.O. Truxton, Inc. products, registered NDC numbers and corresponding lot numbers, to the consumer/user level. C.O. Truxton has not received any complaints for the products listed below. however, due to the initial recall resulting from a label mix-up error, out of an abundance of caution, we are recalling all products that were repackaged into a Truxton Incorporated label. (Source: Food and Drug Administration)
Source: Food and Drug Administration - May 8, 2017 Category: Food Science Source Type: news

C.O. Truxton, Inc. Issues Voluntary Nationwide Recall of Phenobarbital 15 mg Tablets, USP due to Labeling Error on Declared Strength
Bellmawr, New Jersey, C.O. Truxton, Inc. is voluntarily recalling lot 70952A of Phenobarbital Tablets, USP, 15 mg, to the consumer/user level. The manufacturer received a confirmed customer complaint that a bottle labeled as phenobarbital 15 mg was found to contain phenobarbital 30 mg tablets. (Source: Food and Drug Administration)
Source: Food and Drug Administration - April 21, 2017 Category: Food Science Source Type: news

PHENOBARBITAL Tablet [Sterling-Knight Pharmaceuticals, LLC]
Updated Date: Mar 30, 2017 EST (Source: DailyMed Drug Label Updates)
Source: DailyMed Drug Label Updates - March 30, 2017 Category: Drugs & Pharmacology Source Type: news

Dying To Go To Heaven: What The Heaven’s Gate Suicides Teach Us About Islamic Martyrdom
It was 20 years ago this week, March 20-26, 1997, that 39 members of the Heaven’s Gate cult “graduated” from this life to ascend to the UFO mothership that they believed would take them to an extraterrestrial paradise. I’ll never forget it. I was on book tour for Why People Believe Weird Things, and neither I nor any of my peers who study belief systems had ever heard of the cult. It was hard to fathom. Now, as I look back 20 years later, I believe the mass suicide has a deeper lesson that goes far beyond the confines of New Age fringe cults, and has relevance to understanding the motivations o...
Source: Science - The Huffington Post - March 24, 2017 Category: Science Source Type: news

Donnatal Extentabs (Belladonna Alkaloids, Phenobarbital) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 3, 2017 Category: Drugs & Pharmacology Source Type: news

A Quick Guide to Getting Enough Vitamin D
Shanna R. Levine, MD Instructor of General Internal Medicine The Mount Sinai Hospital A Quick Guide to Getting Enough Vitamin D If you are like many of my patients, you may be wondering, "Am I getting enough vitamin D?" This is a valid concern, because vitamin D plays a very important role in overall health and, in fact, many people do not get enough. The Centers for Disease Control and Prevention estimates that about one-third of Americans have insufficient levels. The good news is that sources of this vitamin are easily accessible. Why Is Vitamin D Important? Vitamin D helps the body absorb calcium from the...
Source: Healthy Living - The Huffington Post - January 30, 2017 Category: Consumer Health News Source Type: news

Seizures in the Preterm Neonate
Preterm infants are at high risk for central nervous system injury, with seizures occurring in 6% to 48% of this population. Seizures are more likely to contribute to adverse neurodevelopmental outcomes in preterm infants. Preterm infants are also more likely to have subclinical seizures; therefore, electrographic detection is essential for their diagnosis. Once identified, seizures are traditionally treated with phenobarbital, but newer-generation antiepileptic medications have growing evidence for safety and efficacy. The treatment of seizures may also affect neurodevelopmental outcome. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - January 1, 2017 Category: Pediatrics Authors: Rao, L. M., Marcuccilli, C. J. Tags: Pediatric Drug Labeling Update Articles Source Type: news

PHENOBARBITAL Tablet [Major Pharmaceuticals]
Updated Date: Nov 29, 2016 EST (Source: DailyMed Drug Label Updates)
Source: DailyMed Drug Label Updates - November 29, 2016 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [REMEDYREPACK INC.]
Updated Date: Oct 31, 2016 EST (Source: DailyMed Drug Label Updates)
Source: DailyMed Drug Label Updates - October 31, 2016 Category: Drugs & Pharmacology Source Type: news

Feline Pancreatitis
Feline pancreatitis is inflammation of a cat's pancreas that can disrupt its normal functions and cause other symptoms as well. An inflamed pancreas is a serious problem, because the organ serves two vital functions in the body. It produces hormones -- insulin and glucagon -- that balance blood sugar. It also produces digestive enzymes such as amylase, lipase, and proteases, which enable the body to use carbohydrates, fats and proteins for energy. Symptoms of Pancreatitis in Cats In cats with pancreatitis, there are few overt symptoms. The most common signs are lethargy and lack of appetite. Since cats naturally sleep a ...
Source: Healthy Living - The Huffington Post - August 2, 2016 Category: Consumer Health News Source Type: news

PHENOBARBITAL Liquid [Rising Pharmaceuticals]
Updated Date: Jun 10, 2016 EST (Source: DailyMed Drug Label Updates)
Source: DailyMed Drug Label Updates - June 10, 2016 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [REMEDYREPACK INC.]
Updated Date: May 31, 2016 EST (Source: DailyMed Drug Label Updates)
Source: DailyMed Drug Label Updates - May 31, 2016 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [REMEDYREPACK INC.]
Updated Date: May 13, 2016 EST (Source: DailyMed Drug Label Updates)
Source: DailyMed Drug Label Updates - May 13, 2016 Category: Drugs & Pharmacology Source Type: news

PHENOHYTRO (Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate, Scopolamine Hydrobromide) Tablet [Winder Laboratories, LLC]
Updated Date: Mar 1, 2016 EST (Source: DailyMed Drug Label Updates)
Source: DailyMed Drug Label Updates - March 1, 2016 Category: Drugs & Pharmacology Source Type: news

Severe bupropion overdose and ECMO: two great saves
ChaNaWiT/shutterstock.com 3.5 out of 5 stars Two Cases of Refractory Cardiogenic Shock Secondary to Bupropion Successfully Treated with Veno-Arterial Extracorporeal Membrance Oxygenation. Heise CW et al. J Med Toxicol 2016 Feb 8 [Epub Ahead of Print] Abstract This awesome, exciting paper from Banner University Medical Center in Phoenix describes two teenagers with severe bupropion overdose who survived refractory cardiac arrest after veno-arterial extracorporeal membrane oxygenation (VA-ECMO): Case 1: A 15-year-old girl was brought to hospital after ingesting up to 90 150-mg bupropion tablets. She had a seiz...
Source: The Poison Review - February 12, 2016 Category: Toxicology Authors: Leon Tags: Medical burpropion ECMO extracorporeal membrane oxygenation Source Type: news

PHENOBARBITAL Tablet [West-Ward Pharmaceuticals Corp]
Updated Date: Feb 12, 2016 EST (Source: DailyMed Drug Label Updates)
Source: DailyMed Drug Label Updates - February 12, 2016 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [E5 Pharma, LLC]
Updated Date: Jan 27, 2016 EST (Source: DailyMed Drug Label Updates)
Source: DailyMed Drug Label Updates - January 27, 2016 Category: Drugs & Pharmacology Source Type: news

Donnatal Tablets (Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate, Scopolamine Hydrobromide Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 11, 2016 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [E5 Pharma, LLC]
Updated Date: Jan 8, 2016 EST (Source: DailyMed Drug Label Updates)
Source: DailyMed Drug Label Updates - January 8, 2016 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [Cardinal Health]
Updated Date: Nov 4, 2015 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 4, 2015 Category: Drugs & Pharmacology Source Type: news

DONNATAL (Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate, Scopolamine Hydrobromide) Tablet [PD-Rx Pharmaceuticals, Inc.]
Updated Date: Aug 25, 2015 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - August 25, 2015 Category: Drugs & Pharmacology Source Type: news

DONNATAL (Phenobarbital) Elixir [Unit Dose Services]
Updated Date: Jul 29, 2015 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - July 29, 2015 Category: Drugs & Pharmacology Source Type: news

What is the Epidemiology of SMA Syndrome?
Discussion Superior mesenteric artery syndrome (SMAS) is caused by the compression of the superior mesenteric artery (SMA) against the 3rd part of the duodenum creating a proximal intestinal obstruction. It is relatively rare and can be hard to distinguish from other causes of intestinal obstruction. Normally the SMA arises from the anterior aorta around the L1 vertebra. It extends anteriorly and caudally into the mesentery of the small bowel. The angle between the SMA and aorta is called the aortomesenteric angle and is usually 38-65°. The distance between the SMA and aorta is usually 10-20 mm. Within the aortomesent...
Source: PediatricEducation.org - June 1, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

“I got a bike!”: Adaptive bike brings freedom to boy with cerebral palsy
Seven-year-old Hunter Ripley is a boy of few words. There’s a rare “bye-bye” to his mother as he sets off for school and an occasional “whee” when he’s pushed on his adaptive swing.  So when Hunter screamed, “I got a bike!” at the local pool where he does aquatic therapy every Thursday evening, everyone in the pool went silent. “Then the cheering started,” recalls his mother Bekah Ripley. In February, Bekah and her husband Bart learned about The Great Bike Giveaway, a national contest in which children with special needs can win their own adaptive bike. In or...
Source: Thrive, Children's Hospital Boston - May 5, 2015 Category: Pediatrics Authors: Lisa Fratt Tags: Orthopedics Our patients’ stories Source Type: news

PHENOBARBITAL Elixir [Qualitest Pharmaceuticals]
Updated Date: Mar 5, 2015 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - March 5, 2015 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [DIRECT RX]
Updated Date: Jan 29, 2015 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - January 29, 2015 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [ECI Pharmaceuticals, LLC]
Updated Date: Nov 24, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 24, 2014 Category: Drugs & Pharmacology Source Type: news

DONNATAL (Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate, Scopolamine Hydrobromide) Elixir [Concordia Pharmaceuticals Inc.]
Updated Date: Nov 18, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 18, 2014 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [West-Ward Pharmaceutical Corp]
Updated Date: Oct 21, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 21, 2014 Category: Drugs & Pharmacology Source Type: news

DONNATAL (Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate, Scopolamine Hydrobromide) Tablet [Concordia Pharmaceuticals Inc.]
Updated Date: Oct 15, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 15, 2014 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [American Health Packaging]
Updated Date: Sep 22, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - September 22, 2014 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [Bryant Ranch Prepack]
Updated Date: Jul 25, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - July 25, 2014 Category: Drugs & Pharmacology Source Type: news

DONNATAL (Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate, Scopolamine Hydrobromide) Tablet [Carilion Materials Management]
Updated Date: Jul 7, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - July 7, 2014 Category: Drugs & Pharmacology Source Type: news

PHENOBARBITAL Tablet [Qualitest Pharmaceuticals]
Updated Date: Jun 30, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - June 30, 2014 Category: Drugs & Pharmacology Source Type: news

ME-PB-HYOS (Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate And Scopolamine Hydrobromide) Tablet [Method Pharmaceuticals, Inc.]
Updated Date: Jun 2, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - June 2, 2014 Category: Drugs & Pharmacology Source Type: news

ME-PB-HYOS (Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate And Scopolamine Hydrobromide) Elixir [Method Pharmaceuticals, Inc.]
Updated Date: Jun 2, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - June 2, 2014 Category: Drugs & Pharmacology Source Type: news

DONNATAL (Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate, Scopolamine Hydrobromide) Tablet [RxPak Division Of McKesson Corporation]
Updated Date: May 27, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - May 27, 2014 Category: Drugs & Pharmacology Source Type: news

Episode #4: Poisoning and the diagnosis of brain death
Conclusion: unclear how long to wait before pronouncing brain death as many factors such as pharmacogenetics can alter normal metabolism   Summary Drug overdose can mimic brain death Be especially cautious in overdose involving the scary B’s: baclofen, barbiturate, benzodiazepine The 3-5 half life rule for drug clearance cannot be applied in the cases of overdose Half lives are measured at therapeutic levels Multiple other factors can alter metabolism in overdoses, such as pharmacogenetics, and cross reactivity with other ingestants Consult a toxicologist if there is any question regarding possible overdose...
Source: The Poison Review - May 20, 2014 Category: Toxicology Authors: LeonThe Poison Review Tags: Podcast Source Type: news

PHENOBARBITAL Tablet [McKesson Packaging Services Business Unit Of McKesson Corporation]
Updated Date: Feb 5, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - February 5, 2014 Category: Drugs & Pharmacology Source Type: news

DONNATAL (Phenobarbital Elixir) Elixir [AvKARE, Inc.]
Updated Date: Feb 5, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - February 5, 2014 Category: Drugs & Pharmacology Source Type: news

DONNATAL (Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate, Scopolamine Hydrobromide) Tablet [AvKARE, Inc.]
Updated Date: Jan 6, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - January 6, 2014 Category: Drugs & Pharmacology Source Type: news

Case Conference: agitated delirium from snorting “bath salts”
This article is part of the New England Journal of Medicine‘s “Case Records of the Massachusetts General Hospital” series. There is a very good discussion of the initial approach and differential diagnosis for a patient who presents with “agitation, delirium abnormal vital signs, and reports he had taken a toxic substance.” However, I find some of the management decisions puzzling. The patient was initially treated with fomepizole and sodium thiosulfate. Although toxic alcohols and cyanide are certainly in the differential for metabolic acidosis, that seems to me a case of treating the lab val...
Source: The Poison Review - December 27, 2013 Category: Toxicology Authors: Leon Tags: Medical agitated delirium bath salts case records of the massachusetts general hospital methcathinone Source Type: news

July eFactor
Birnbaum headlines Detroit Community Forum Leaders address Association of Public Health Laboratories NIEHS spurs investigation into the health effects of e-waste recycling Scholars Connect program welcomes class of 2013-2014 Agencies award $100,000 to winner of health and technology challenge Office of Scientific Information Management takes shape NIEHS launches website redesigned for mobile devices WETP workshop identifies strategies to promote effective safety cultures Former postdoc named chief research officer for NIH research partner NIEHS brings public health perspective to climate change policy forum Keyno...
Source: Environmental Factor - NIEHS Newsletter - July 9, 2013 Category: Environmental Health Source Type: news

How to survive the shortage of injectable sodium bicarbonate
Sodium bicarbonate is probably the most versatile antidote in the medical toxicologist’s armamentarium. The list of poisons for which bicarb is indicated lincludes: Sodium-channel blockers (including tricyclic antidepressants) Salicylates phenobarbital methotrexate ethylene glycol methanol chlorine gas inhalation It is, therefore, distressing that bicarb is among the many pharmaceuticals that have recently been in short supply. To read my Emergency Medicine News column on this problem — and find out what to do when sodium bicarbonate is simply not available, click here. (Source: The Poison Review)
Source: The Poison Review - July 9, 2013 Category: Toxicology Authors: Leon Tags: Medical drug shortage Emergency Medicine News sodium bicarbonate toxicology rounds Source Type: news

Prolonged toxic coma and anisocoria secondary to doxepin, lorazepam and phenobarbital poisoning--case study - Kołodziej M, Majewska M, Krajewska A, Szponar J.
Doxepin is a tricyclic antidepressant from the group of dibenzoxepines. Apart from the antidepressant effect, it has also the sedative and anxiolytic effect, so it is used in the treatment of anxiety disorder in the course of psychosis, organic diseases an... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - June 26, 2013 Category: Global & Universal Tags: Poisoning Source Type: news

UK firm halts sale of convulsion drug to Arkansas over death row use
UK-based pharmaceutical company Hikma has stopped supplying convulsion drug phenobarbital to Arkansas in the US to prevent it being used in state executions. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - May 16, 2013 Category: Pharmaceuticals Source Type: news

British maker of death penalty drugs adds new restrictions for US buyers
Hikma Pharmaceuticals moves to avoid 'unintended purposes' for drugs amid growing European boycott on sale to the USA drug manufacturer based in Britain has vowed to add new restrictions to sales of its products in the US after it was revealed that it sold a batch of barbiturate to the Arkansas department of corrections, which intended to use it in executions.Hikma Pharmaceuticals has promised to put in place "concrete steps to restrict the supply of its products for unintended uses" following the disclosure by the legal action charity Reprieve that a wholly owned subsidiary in the US had sold injectable phenobar...
Source: Guardian Unlimited Science - May 15, 2013 Category: Science Authors: Ed Pilkington Tags: United States Capital punishment World news Pharmaceuticals industry guardian.co.uk Europe Drugs UK news Arkansas Source Type: news

[Perspective] Old Dance with a New Partner: EGF Receptor as the Phenobarbital Receptor Mediating Cyp2B Expression
The direct interaction of phenobarbital with the epidermal growth factor receptor reveals a new network interface in nuclear receptor signaling. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - May 12, 2013 Category: Science Authors: Sharon A. Meyer, Randy L. Jirtle Source Type: news

[Research Article] Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling
The epidermal growth factor receptor is an unexpected target of the barbiturate phenobarbital. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - May 7, 2013 Category: Science Authors: Shingo Mutoh, Mack Sobhany, Rick Moore, Lalith Perera, Lee Pedersen, Tatsuya Sueyoshi, Masahiko Negishi Source Type: news

What Causes Constipation?
Discussion Constipation generally is defined as infrequent or painful defecation. Constipation can be very disturbing to the patient and family who believe the stools are too infrequent, too hard or too difficult to pass. Most children develop constipation after the child begins to associate pain (e.g. a hard bowel movement) with defecation. The child then begins to withhold the stools trying to decrease the defecation discomfort. As stool withholding continues, the rectum dilates and gradually accommodates with the normal defecation urge disappearing. Passing large hard stools infrequently reinforces the defecation pain. ...
Source: PediatricEducation.org - February 25, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news