Relating pancreatic ductal adenocarcinoma tumor samples and cell lines using gene expression data in translational research.

In this study, we compared the gene expression profile of 178 PDAC tumor samples from The Cancer Genome Atlas and 44 pancreatic cancer cell lines from Cancer Cell Line Encyclopedia. We showed that all pancreatic cancer cell lines resemble PDAC tumors but the correlation is different. Our study will be used to guide the selection of PDAC cell lines. PMID: 29729710 [PubMed - in process]
Source: Cellular and Molecular Biology - Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research