Enrichment of Female Germline Stem Cells from Mouse Ovaries Using the Differential Adhesion Method

Conclusions: The differential adhesion method provides a more feasible approach and is an easier procedure to establish FGSC lines than traditional methods. The AKT pathway plays an important role in regulation of the proliferation and maintenance of FGSCs. These findings could help promote stem cell studies and provide a better understanding of causes of ovarian infertility, thereby providing potential treatments for infertility.Cell Physiol Biochem 2018;46:2114 –2126
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research