Association of Protein Kinase B (AKT) DNA Hypermethylation with Maintenance Atypical Antipsychotic Treatment in Patients with Bipolar Disorder

ConclusionOverall, our findings suggest that the AKT gene is differentially methylated in the skeletal muscle of patients taking atypical antipsychotics or mood stabilizer maintenance therapy. These results may direct future approaches to reduce the harmful adverse effects of atypical antipsychotic treatment.This article is protected by copyright. All rights reserved.

Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - February 1, 2018 Category: Drugs & Pharmacology Authors: Kyle J. Burghardt, Berhane Seyoum, Sabrina Dass, Elani Sanders, Abdullah Mallisho, Zhengping Yi Tags: Original Research Article Source Type: research