Clusterin Reduces Cold Ischemia-Reperfusion Injury in Heart Transplantation Through Regulation of NF-kB Signaling and Bax/Bcl-xL Expression

Conclusion: Clusterin is a promising target for preventing cold I/R injury in heart transplantation. This study also shows that the resultant protective effects of clusterin are mediated by NF- κB signaling and Bax/Bcl-xL expression.Cell Physiol Biochem 2018;45:1003 –1012

https://www.karger.com/Article/FullText/487295

Source: Cellular Physiology and Biochemistry - February 9, 2018 Category: Cytology Source Type: research