Non ‐alcoholic Fatty Liver Disease is associated with stroke severity and progression of brainstem infarctions
Abstract BackgroundNon‐alcoholic fatty liver disease (NAFLD) is closely correlated to visceral obesity, dyslipidaemia, insulin resistance, and type 2 diabetes mellitus (T2DM). We sought to assess the association between a specific stroke subgroup, brainstem infarctions (BSIs), and NAFLD. Furthermore, we evaluated whether NAFLD is an independent risk factor in patients with BSIs. MethodsNAFLD was assessed in 306 radiologically confirmed BSIs patients via liver ultrasound. Differences between patients with and without NAFLD were compared. Data associated with stroke severity and progression after admission was collected. ResultsNAFLD was found in 130 (42.5%) patients with acute BSIs; 58 (19.0%) had National Institutes of Health Stroke Scale (NIHSS) scores>7, and 57 (18.6%) had progression after admission. Initial NIHSS scores, incidence of progression and stroke severity, and modified Rankin Scale (mRS) scores at discharge were significantly higher in patients with NAFLD than those without NAFLD. NAFLD was associated with stroke severity (Cox Regression, HR 2.243, CI 1.254–4.013, p
Publication date: June 2020Source: Accident Analysis &Prevention, Volume 140Author(s): Ankit Kumar Yadav, Nagendra R. Velaga
Publication date: Available online 28 March 2020Source: Materials Today: ProceedingsAuthor(s): S. Godwin Barnabas, S. Valai Ganesh, V. Sivakumar, P. Muthukumar, A. Dhinesh Raja, K. Hariharan
Publication date: Available online 28 March 2020Source: Journal of Clinical NeuroscienceAuthor(s): Akemi Hioka, Yoshiteru Tada, Keiko Kitazato, Naoki Akazawa, Yasushi Takagi, Shinji Nagahiro
Publication date: Available online 28 March 2020Source: Journal of Clinical NeuroscienceAuthor(s): Tugba Ozsoy-Unubol, Yeliz Bahar-Ozdemir, Ilker Yagci
Authors: Zhang Y, Bi L, Hu Z, Cao W, Zhuang D Abstract It has been found that>90% of oral cancer patients suffer from squamous cell carcinoma (SCC). The 5-year survival rate of SCC is ~50%, despite the availability of different treatments. Sonodynamic therapy (SDT) has been developed as a novel therapy for cancer, resisting bacterial infection and inhibiting atherosclerotic plaque progression. The present study investigated the efficacy of hematoporphyrin monomethyl ether (HMME)-mediated SDT on the A-253 epidermoid cancer cell line. The cytotoxicity of HMME and the survival rate of cells following SDT were exami...
PMID: 32213150 [PubMed - in process]
Authors: Kawada T PMID: 32216510 [PubMed - as supplied by publisher]
CONCLUSION: A machine learning-based approach could provide better SI prediction performance compared to a conventional LR-based model. These may help primary care physicians to identify patients at risk of SI and will facilitate the early prevention of suicide. PMID: 32213803 [PubMed - as supplied by publisher]
Authors: Shibayama Y, Wada N, Baba S, Obara S, Sakai H, Usubuchi H, Terae S, Nakamura A, Atsumi T Abstract Patients with primary aldosteronism (PA) are complicated by metabolic syndrome more frequently than those without PA. Hyperaldosteronism has been reported to be associated with a higher prevalence of non-alcoholic fatty liver disease (NAFLD). We aimed to clarify the risk factors for hepatic steatosis in the two subtypes of PA, comparing the status of hepatic steatosis in each of these subtypes. This was a retrospective observational study. We enrolled patients with an aldosterone producing adenoma (APA) (n = 3...
Creatinine/(cystatin C × body weight) ratio is associated with skeletal muscle mass index. Endocr J. 2020 Mar 26;: Authors: Nishida K, Hashimoto Y, Kaji A, Okamura T, Sakai R, Kitagawa N, Osaka T, Hamaguchi M, Fukui M Abstract We have previously reported that the creatinine (Cre) to cystatin C (CysC) ratio is associated with height-adjusted skeletal muscle mass index (SMI). However, weight-adjusted SMI is reported to be a more useful marker of insulin sensitivity than height-adjusted SMI. Thus, we hypothesized that the creatinine to (cystatin C × body weight [BW]) relationship (Cre/[CysC &t...
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