Steep rise in antibiotic use for coughs and colds

ConclusionThis cross-sectional study has found the proportion of people with coughs and colds that are prescribed antibiotics rose from 36% in 1999 to 51% in 2011 – an increase of approximately 40%. This is despite the publication of guidance recommending that GPs do not prescribe antibiotics for coughs and colds. It also found substantial variation between different GP practices, with 10% of practices prescribing antibiotics for less than 32% of cases and 10% of practices prescribing antibiotics for more than 65% of cases, suggesting that substantially lower rates of prescribing could be achieved.The study also looked at antibiotic prescription for sore throats, UTIs and otitis media. Antibiotic prescription for sore throats fell, and prescription of recommended antibiotics increased. Over the study period, more women with UTIs were prescribed the recommended short course of antibiotics. For otitis media, the proportion of cases that were prescribed an antibiotic was broadly unchanged, and prescriptions for recommended antibiotics rose.There was variation between GP practices in antibiotic prescription for these conditions, suggesting that further improvements in antibiotic prescription could be made. In conclusion, this study suggests there is a need to improve the way antibiotics are prescribed.Analysis by Bazian. Edited by NHS Choices. Follow Behind the Headlines on Twitter. Join the Healthy Evidence forum. Links To The Headlines New figures reve...
Source: NHS News Feed - Category: Consumer Health News Tags: Medical practice Medication Source Type: news

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ConclusionSILPE can be safely incorporated in the management of patients with PM. It is a safe and feasible staging tool, allowing for preventing unwarranted laparotomy for patients not deemed candidate for CRS/HIPEC. Even though it may underestimate PCI, SILPE accurately predicts the possibility of CCR.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
ConclusionThe re-excision rate following NAC is almost twice that of patients who underwent primary operative management. Her2+  and triple-negative tumors have lower re-excision rates and may represent a selected cohort most suitable for BCS. Patients with invasive lobular carcinoma or ER+ disease have significantly higher rates of margin positivity, and these patients should be considered for a cavity shave during prim ary surgery to reduce the rates of re-excision.
Source: World Journal of Surgery - Category: Surgery Source Type: research
Conclusion: After the third relapse of HGSC, cytotoxic chemotherapy did not prolong survival but was associated with substantially increased healthcare costs. PMID: 32223298 [PubMed - as supplied by publisher]
Source: Journal of Comparative Effectiveness Research - Category: General Medicine Tags: J Comp Eff Res Source Type: research
Conditions:   Clinical Stage IV Gastric Cancer AJCC v8;   Clinical Stage IVA Gastric Cancer AJCC v8;   Clinical Stage IVB Gastric Cancer AJCC v8;   Malignant Uterine Neoplasm;   Metastatic Colorectal Carcinoma;   Metastatic Gastric Carcinoma;   Metastatic Malignant Neoplasm in  the Peritoneum;   Metastatic Ovarian Carcinoma;   Pathologic Stage IV Gastric Cancer AJCC v8;   Peritoneal Carc...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Anatomic Stage I Breast Cancer AJCC v8;   Anatomic Stage IA Breast Cancer AJCC v8;   Anatomic Stage IB Breast Cancer AJCC v8;   Anatomic Stage II Breast Cancer AJCC v8;   Anatomic Stage IIA Breast Cancer AJCC v8;   Anatomic Stage IIB Breast Cancer AJCC v8 ;   Anatomic Stage III Breast Cancer AJCC v8;   Anatomic Stage IIIA Breast Cancer AJC...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Hospitals have spent the past few weeks racing to respond to the growing COVID-19 crisis, supplementing shortages of equipment, calling back retired personnel, and transforming entire hospital wings to care for infected patients. So when Congress included $100 billion in the stimulus package passed last week to help hospitals and other health care providers address the pandemic, it was seen as much-needed assistance. But that’s not the whole story, health care experts say. Due to the patchwork nature of the U.S. health care system, a huge chunk of those emergency funds likely won’t go to lifesaving care or equi...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
CONCLUSION: Our results showed increased percentages of regulatory T cells in pediatric ALL patients despite chemotherapy, which might be compromising the anti-leukemic cellular immune response. PMID: 32224544 [PubMed - in process]
Source: Iranian Journal of Immunology - Category: Allergy & Immunology Tags: Iran J Immunol Source Type: research
Tuesday, March 10. Speech-language pathologist Fatima Warren was grocery shopping with her grandmother when she first noticed the painful body aches. Chalking it up to the rainy day and an earlier workout, she ran a hot bath. Wednesday, March 11. Warren woke up with chills, fever, and worsening aches. She drove straight to the closest ER in her hometown of Lexington, Kentucky. There, staff ran numerous tests, but not for COVID-19. The 45-year-old didn’t qualify because she hadn’t traveled outside the country and couldn’t name a contact with the virus. Thursday, March 12. Worried about infecting her 13-yea...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - Category: Speech-Language Pathology Authors: Tags: Slider Speech-Language Pathology Uncategorized acute care Cognitive Rehabilitation Dysphagia FEES Health Care MBSS personal protective equipment skilled nursing facilities Swallowing Disorders Source Type: blogs
Purpose of review Given the worldwide shortage of Bacillus Calmette–Guérin (BCG), we review the efficacy of alternative BCG application schedules, doses or strains and intravesical chemotherapy in patients with nonmuscle-invasive bladder cancer (NMIBC). Recent findings Modifying BCG schedules by reducing the dose is preferable to reducing the frequency of BCG that increases recurrence rates and should be avoided if possible. Changing the BCG substrain represents a reasonable option, as current evidence does not suggest different oncological outcomes with specific BCG substrains. Mitomycin C (MMC) alone is...
Source: Current Opinion in Urology - Category: Urology & Nephrology Tags: BLADDER CANCER: Edited by Juan Palou and Óscar Rodríguez Faba Source Type: research
Purpose of review To report the available information on the current status and future direction of the use of checkpoint inhibitors as novel immunotherapeutic agents in bladder cancer. Recent findings In the past 3 years, five immunotherapies targeting programmed cell death 1 (Pembrolizumab and Durvalumab) or programmed cell death-ligand 1 (PD-L1) (Atezolizumab, nivolumab and Avelumab) pathways have been approved in second-line setting for patients who progressed during or after cisplatin-based chemotherapy. According to the most recent update, these patients should be PD-L1-positive to be eligible for immunotherapy....
Source: Current Opinion in Urology - Category: Urology & Nephrology Tags: BLADDER CANCER: Edited by Juan Palou and Óscar Rodríguez Faba Source Type: research
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