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These 3 Superbugs Pose The Greatest Risk To Human Health
The World Health Organization is issuing a warning about a group of deadly bacteria: Recently, the WHO released its first-ever list of “priority pathogens,” a list of antibiotic-resistant bacteria that the organization says pose the greatest threat to human health. The list is divided into three categories: critical-, high- and medium-priority. Three pathogens made it into the critical-priority group. These bacteria are resistant to multiple antibiotics and pose a high risk to people in hospitals and nursing homes, the WHO says. Multidrug-resistant bacteria, sometimes called “superbugs,” are a ...
Source: Science - The Huffington Post - March 23, 2017 Category: Science Source Type: news

Prevpac (Lansoprazole, Amoxicillin and Clarithromycin) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 29, 2016 Category: Drugs & Pharmacology Source Type: news

clarithromycin, Biaxin
Title: clarithromycin, Biaxin Category: Medications Created: 12/31/1997 12:00:00 AM Last Editorial Review: 7/29/2016 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - July 29, 2016 Category: Drugs & Pharmacology Source Type: news

Two Weeks of PAM Triple Therapy for H pylori as Effective as PACTwo Weeks of PAM Triple Therapy for H pylori as Effective as PAC
Triple therapy combining a proton-pump inhibitor (PPI), amoxicillin, and high-dose metronidazole (PAM) given thrice daily for 14 days provides Helicobacter pylori eradication rates similar to those with triple-therapy regimens containing clarithromycin (PAC), according to a new report. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 19, 2016 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Biaxin, Biaxin XL (Clarithromycin) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 28, 2016 Category: Drugs & Pharmacology Source Type: news

New Lyme Disease Study Reveals Strong Reporting Bias
This study is a useful contribution to ongoing investigations of how to treat ongoing Lyme disease symptoms among patients who have received the standard 28-day course of doxycycline and continue to experience severe symptoms commonly associated with Lyme disease. This study is also significant because, unlike the majority of Lyme disease-related studies published in peer-reviewed medical journals, it made international headlines in mainstream news outlets. Some publications that specialize in medical and health-related stories covered the story appropriately, such as Medscape, whose headline reads, "Post-Treatment Ly...
Source: Healthy Living - The Huffington Post - April 8, 2016 Category: Consumer Health News Source Type: news

Cardiovascular outcomes associated with use of clarithromycin: population based study
This research article looks at current clarithromycin use associated with increased risk of myocardial infarction, arrhythmia, and death compared to current amoxicillin use in adults. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 11, 2016 Category: Consumer Health News Source Type: news

Clarithromycin and Short-term Risk of Cardiovascular EventsClarithromycin and Short-term Risk of Cardiovascular Events
Clarithromycin is associated with an increased short-term risk of cardiovascular morbidity, especially in older patients and those with hypertension or diabetes, according to a new population-based study. Reuters Health Information (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - January 22, 2016 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

Two commonly used antibiotics OK during pregnancy
Stephen FellerMONTREAL, Oct. 30 (UPI) -- Researchers found that two of the most commonly used antibiotics -- azithromycin and clarithromycin -- are safe for women to take during pregnancy. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 30, 2015 Category: Consumer Health News Source Type: news

Your NEJM Group Today: Torture at CIA "Black Sites", Half Dose of Clarithromycin for H. pylori, New York EM Opportunities (FREE)
By the Editors NEJM Group offers so many valuable resources for practicing clinicians. Here's what we chose for you today:NEJM Clinical Practice Center: Perspective: According … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - June 15, 2015 Category: Primary Care Source Type: news

'Modest' Elevated Risk With Clarithromycin Plus Some Statins 'Modest' Elevated Risk With Clarithromycin Plus Some Statins
It was seen for the antibiotic with statins not metabolized via cytochrome P450 3A4, researchers say. Though small, the added risk may be important in practice given how often the drugs are combined. Heartwire (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - December 29, 2014 Category: Cardiology Tags: Cardiology News Source Type: news

Combining statin with antibiotic can 'increase risk of adverse events'
Combining the antibiotic clarithromycin with some statins increases the risk of adverse events, which may lead to hospital admission in older patients, according to Canadian researchers. (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - December 23, 2014 Category: Nursing Source Type: news

Clarithromycin Plus Certain Statins Associated with Hospitalization Risk in Older Adults (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH Clarithromycin — when coprescribed with some statins in older adults — is associated with increased risks for adverse outcomes including mortality, according to an observational study … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - December 23, 2014 Category: Primary Care Source Type: news

Clarithromycin-statin mix can cause drug interactions, requiring hospitalization
The combination of the common antibiotic clarithromycin with some statins increases the risk of adverse events, which may require hospital admission for older people, according to a new study. Statins, used to lower cholesterol, are one of the most widely prescribed drugs, with projections estimated at more than 1 billion people around the globe. Although uncommon, severe adverse events can occur in some patients when certain medications interact with the statin and affect the way it is metabolized. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 22, 2014 Category: Science Source Type: news

Certain Antibiotic/Statin Combos May Be Unsafe Mix
Use of clarithromycin along with the cholesterol-lowering meds had higher risk of side effects Source: HealthDay Related MedlinePlus Pages: Antibiotics, Drug Reactions, Statins (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - December 22, 2014 Category: Consumer Health News Source Type: news

Study links common antibiotic to heart deaths
New research has uncovered a correlation between the antibiotic Clarithromycin and an increase in heart deaths. Despite the connection, researchers say the risk is small, and that doctors shouldn't alter the way they administer the drug. CBS News' Michelle Sigona reports. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - August 20, 2014 Category: Consumer Health News Source Type: news

Increased Heart Risk Linked To Popular Antibiotic
Acute use of the popular macrolide antibiotic clarithromycin has been linked to a small but significant increase in cardiac death. In a report in the BMJ, researchers in Denmark analyzed the effects over a 14-year period of the acute use of penicillin V, roxithromycin, and clarithromycin. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 20, 2014 Category: Pharmaceuticals Authors: Larry Husten Source Type: news

Clarithromycin May Boost Risk of Cardiac Death (CME/CE)
(MedPage Today) -- The antibiotic clarithromycin was associated with a significantly increased risk for cardiac death, a large Danish study found. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - August 20, 2014 Category: Primary Care Source Type: news

Common antibiotic linked to 'tiny' rise in heart deaths
Conclusion The conclusion that the risk of cardiac death during the use of clarithromycin is 76% higher than that for penicillin V was based on a small number of cardiac deaths. In fact, it occurred during 0.01% of prescriptions of clarithromycin, compared with 0.005% during prescriptions for penicillin V. A death rate just a bit higher than a very small death rate is still very small. This means that from an individual point of view, the risk of cardiac death from taking either antibiotic is minimal. This study does not prove clarithromycin caused any cardiac deaths. It only showed a very small increa...
Source: NHS News Feed - August 20, 2014 Category: Consumer Health News Tags: Medication Medical practice Source Type: news

Antibiotic Might Raise Heart Risks for Some
People with underlying heart rhythm disorders may want to avoid clarithromycin, study suggests Source: HealthDay Related MedlinePlus Pages: Antibiotics, Arrhythmia (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - August 20, 2014 Category: Consumer Health News Source Type: news

Antibiotic Clarithromycin 'linked to heart deaths'
A British study found clarithromycin, which is widely used for treating common bacterial infections, is linked with a 76 per cent higher risk of heart deaths. (Source: the Mail online | Health)
Source: the Mail online | Health - August 20, 2014 Category: Consumer Health News Source Type: news

Antibiotic Might Raise Heart Risks for Some
People with underlying heart rhythm disorders may want to avoid clarithromycin, study suggests (Source: WebMD Health)
Source: WebMD Health - August 20, 2014 Category: Consumer Health News Source Type: news

Increased Cardiac Risk Linked to Clarithromycin (FREE)
By Larry Husten Edited by Lorenzo Di Francesco, MD, FACP, FHM Acute use of the popular macrolide antibiotic clarithromycin has been linked to a small but significant increase in cardiac death, according to a BMJ study. Using Danish registries, researchers analyzed the effects … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 20, 2014 Category: Primary Care Source Type: news

Antibiotic link to higher risk of cardiac death
76% higher risk of cardiac death from clarithromycin than penicillin VRelated items from OnMedicaEarly antibiotic exposure linked to obesity Macrolide antibiotics improve symptoms in bronchiectasisProbiotics don’t seem to stave off diarrhoea linked to antibiotics in elderly Cardiovascular safety of antidiabetes drugs in doubtPainkiller raises risk of irregular heartbeat in older people (Source: OnMedica Latest News)
Source: OnMedica Latest News - August 20, 2014 Category: UK Health Source Type: news

Antibiotics and risk of cardiac death
Commenting on the study published in today’s BMJ, Use of clarithromycin and roxithromycin and risk of cardiac death: cohort study, Dr Kieran Hand (PhD), Consultant Pharmacist Anti-Infectives, University Hospital Sou (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - August 19, 2014 Category: Drugs & Pharmacology Source Type: news

Clarithromycin Tied to Risk of Cardiac Death in Cohort StudyClarithromycin Tied to Risk of Cardiac Death in Cohort Study
Current use of clarithromycin, but not roxithromycin, was tied to a small absolute increased risk of cardiac death, compared with taking penicillin V, in a new study. Heartwire (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 19, 2014 Category: Consumer Health News Tags: Cardiology News Source Type: news

Steep rise in antibiotic use for coughs and colds
ConclusionThis cross-sectional study has found the proportion of people with coughs and colds that are prescribed antibiotics rose from 36% in 1999 to 51% in 2011 – an increase of approximately 40%. This is despite the publication of guidance recommending that GPs do not prescribe antibiotics for coughs and colds. It also found substantial variation between different GP practices, with 10% of practices prescribing antibiotics for less than 32% of cases and 10% of practices prescribing antibiotics for more than 65% of cases, suggesting that substantially lower rates of prescribing could be achieved.The ...
Source: NHS News Feed - August 5, 2014 Category: Consumer Health News Tags: Medical practice Medication Source Type: news

UK says Mylan recalls batches of Polish-made antibiotic
LONDON (Reuters) - U.S. drugmaker Mylan is recalling batches of the injectable antibiotic clarithromycin made in Poland due to possible impurities, Britain's healthcare regulator said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - June 19, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

UK says Mylan recalls batches of Indian-made antibiotic
LONDON (Reuters) - U.S. drugmaker Mylan is recalling batches of the injectable antibiotic clarithromycin made in India due to possible impurities, Britain's healthcare regulator said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - June 18, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include the controversy surrounding antibacterial soaps, new high blood pressure guidelines, an interaction between calcium channel blockers and clarithromycin, and no benefits to multivitamins. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 20, 2013 Category: Cardiology Source Type: news

Torsades de Pointes Following Clarithromycin TreatmentTorsades de Pointes Following Clarithromycin Treatment
What factors influence this life threatening adverse event? Expert Review of Cardiovascular Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 4, 2013 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Antibiotic and Calcium-Channel Blocker a Fatal CombinationAntibiotic and Calcium-Channel Blocker a Fatal Combination
Significant -- and avoidable -- hospitalizations and deaths are attributed to interactions between clarithromycin and antihypertensives, coprescriptions that remain common despite warnings. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 13, 2013 Category: Consumer Health News Tags: Nephrology News Source Type: news

Use of calcium-channel blocker and antibiotic associated with small increased risk of kidney injury
Among older adults taking a calcium-channel blocker, simultaneous use of the antibiotic clarithromycin, compared with azithromycin, was associated with a small but statistically significant greater 30-day risk of hospitalization with acute kidney injury, according to a study published by JAMA. The study is being published early online to coincide with its presentation at the American Society of Nephrology's Kidney Week 2013. The commonly used antibiotics clarithromycin and erythromycin are clinically important inhibitors of the enzyme CYP3A4, while azithromycin is much less so... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 12, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Use of calcium-channel blocker and antibiotic associated with small increased risk of kidney injury
(The JAMA Network Journals) Among older adults taking a calcium-channel blocker, simultaneous use of the antibiotic clarithromycin, compared with azithromycin, was associated with a small but statistically significant greater 30-day risk of hospitalization with acute kidney injury, according to a study published by JAMA. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 9, 2013 Category: Global & Universal Source Type: news

Concurrent macrolide antibiotic may increase statin toxicity
Coprescription of clarithromycin or erythromycin with a statin that is metabolized by CYP3A4 increases the risk for statin toxicity in older adults, according to a population-based cohort study. (Source: theHeart.org)
Source: theHeart.org - June 18, 2013 Category: Cardiology Source Type: news

Concurrent Macrolide Antibiotic May Increase Statin ToxicityConcurrent Macrolide Antibiotic May Increase Statin Toxicity
Coprescription of clarithromycin or erythromycin with a statin that is metabolized by CYP3A4 increases the risk for statin toxicity in older adults, according to a population-based cohort study. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 17, 2013 Category: Consumer Health News Tags: Internal Medicine News Source Type: news

Antibiotic Linked to Heart Problems in COPD Patients
Study looked at clarithromycin use for lung conditions, but didn't prove cause-and-effect (Source: WebMD Health)
Source: WebMD Health - March 22, 2013 Category: Consumer Health News Source Type: news

Antibiotic Linked to Heart Problems in COPD Patients
Study looked at clarithromycin use for lung conditions, but didn't prove cause-and-effect Source: HealthDay Related MedlinePlus Pages: Antibiotics, COPD (Chronic Obstructive Pulmonary Disease), Heart Diseases (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 22, 2013 Category: Consumer Health News Source Type: news

Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies
Source: BMJ Area: News There have been concerns about the possibility of harmful effects of widespread macrolide use on cardiovascular morbidity and mortality. Whilst clarithromycin is the macrolide that is used most often in the UK, the authors report that no studies have investigated the long term effect of clarithromycin on cardiovascular events and mortality in patients after acute exacerbations of chronic obstructive pulmonary disease (COPD) or community acquired pneumonia (CAP).  They conducted a secondary analysis of two large prospective cohort studies to investigate the association in these patient groups. T...
Source: NeLM - Cardiovascular Medicine - March 22, 2013 Category: Cardiology Source Type: news

Rapamune (sirolimus) tablets and oral solution - Pfizer Limited - Revised SPC
Source: eMC (electronic Medicines Compendium) Area: Other Library Updates> SPC Changes Section 4.5 Interaction with other medicinal products and other forms of interaction has been updated to include potential interactions with CYP3A4 inhibitors, which may decrease the metabolism of sirolimus and increase sirolimus blood levels. Such inhibitors include e.g. certain antifungals (e.g. clotrimazole, fluconazole, itraconazole, voriconazole), certain antibiotics (e.g.  troleandomycin, telithromycin, clarithromycin), certain protease inhibitors (e.g. ritonavir, indinavir, boceprevir, telaprevir),  nicardipine, brom...
Source: NeLM - SPC Changes - March 1, 2013 Category: Drugs & Pharmacology Source Type: news

Clarithromycin and higher risk of miscarriage
Researchers in Denmark have tied the use of the antibiotic clarithromycin to an increased risk of miscarriage-but not to an increased risk of birth defects. (Source: Modern Medicine)
Source: Modern Medicine - January 10, 2013 Category: Journals (General) Source Type: news

Antibiotic Tied to Higher Risk of Miscarriage (CME/CE)
(MedPage Today) -- Use of the antibiotic clarithromycin (Biaxin) in the first trimester of pregnancy is associated with an increased risk of miscarriage, Danish researchers reported. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 6, 2013 Category: Infectious Diseases Source Type: news