Metformin for endometrial hyperplasia.

CONCLUSIONS: At present, evidence is insufficient to support or refute the use of metformin alone or in combination with standard therapy - specifically, megestrol acetate - versus megestrol acetate alone, for treatment of endometrial hyperplasia. Robustly designed and adequately powered randomised controlled trials yielding long-term outcome data are needed to address this clinical question.
PMID: 29077194 [PubMed - as supplied by publisher]

Source: Cochrane Database of Systematic Reviews - October 27, 2017 Category: General Medicine Authors: Clement NS, Oliver TR, Shiwani H, Sanner JR, Mulvaney CA, Atiomo W Tags: Cochrane Database Syst Rev Source Type: research