Study Finds No Need to Expand Mesothelioma Palliative Care
Earlier palliative care for patients with pleural mesothelioma failed to improve quality of life or extend survival time in a recent study presented at the World Conference on Lung Cancer in Yokohama, Japan. The randomized control study took place in Australia and the United Kingdom, disputing an earlier recommendation by the American Society of Clinical Oncology (ASCO) that called for expanding palliative care for mesothelioma patients. “Blindly offering palliative care to all, that doesn’t appear to be a benefit,” Dr. Fraser Brims, study presenter from Curtin University in Perth, Australia, told Asbestos.com. “The results really went against what many thought would be the case. It was quite surprising.” Pleural mesothelioma is a rare and aggressive cancer caused by exposure to asbestos. There is no definitive cure and most patients live less than 18 months after diagnosis. Palliative care typically focuses on quality of life and relieving symptoms caused by the disease itself or the side effects from the medications used to treat it. No Difference in Quality of Life The study involved 174 mesothelioma patients who were randomly assigned standard of care alone or early specialist palliative care, which involved visits every four weeks. The vast majority of the patients were men with the epithelioid subtype of mesothelioma and had high symptom burden. Median age was 72.6 years, and 60 percent of those studied had at least one cycle of chemother...
Publication date: 15 February 2021Source: Journal of Hazardous Materials, Volume 404, Part BAuthor(s): Yanhua Liu, Yang Li, Shanshan Dong, Lu Han, Ruixin Guo, Yourong Fu, Shenghu Zhang, Jianqiu Chen
Authors: Musio F Abstract INTRODUCTION: Anemia has and will continue to be a central theme in medicine particularly as clinicians are treating a burgeoning population of complex multi-organ system processes. As a result of multiple randomized controlled trials (RCTs), meta-analyses, and societal recommendations overly restrictive paradigms and under-administration of erythropoiesis stimulating agents (ESAs) have likely been followed by clinicians among all specialties. AREAS COVERED: A review of anemia in the context of chronic kidney disease, hematologic malignancies and cancer is presented with focus on the e...
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Authors: Havill J, Smales L PMID: 33032311 [PubMed - in process]
Authors: Matti B, Zargar-Shoshtari K Abstract Prostate cancer represents a significant health burden worldwide. The cancer incidence had substantially increased since the introduction of prostate specific antigen (PSA) in cancer screening. This had led to considerable debates among health professionals and epidemiologists, since PSA as a screening tool seemed to be far from perfect. In New Zealand, the controversy was quite prominent in the last three decades, with some advocating the benefits of screening, while others concerned regarding the risk of harms. With the absence of an organised screening programme and ...
CONCLUSION: This study found that childhood cancer survivors in New Zealand had a high prevalence of developmental dental abnormalities and it identified potential risk factors related to their cancer treatment. Inequitable access to oral rehabilitation for this patient group argues for a mechanism for consistent improved access to publicly funded dental care across district health boards in New Zealand. PMID: 33032302 [PubMed - in process]
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