Radiation and PD-1 inhibition: Favorable outcomes after brain-directed radiation.

CONCLUSIONS: Incorporation of palliative radiation does not preclude favorable outcomes in patients treated with PD-1 inhibitors; patients irradiated after the start of PD-1 inhibition can remain on therapy and demonstrate prolonged survival. Of note, patients irradiated for brain metastases demonstrate favorable outcomes compared with historical controls. PMID: 28662869 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28662869?dopt=Abstract

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - June 26, 2017 Category: Radiology Authors: Pike LRG, Bang A, Ott P, Balboni T, Taylor A, Catalano P, Rawal B, Spektor A, Krishnan M, Cagney D, Alexander B, Aizer AA, Buchbinder E, Awad M, Gandhi L, Hodi FS, Schoenfeld JD Tags: Radiother Oncol Source Type: research