A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use.
CONCLUSIONS: As currently performed, a single TEB is, therefore, mathematically incapable of reliably determining whether an embryo can be transferred or should be discarded. Since a single TEB, as currently performed, apparently is not representative of the complete TE, this study, thus, raises additional concern about the clinical utilization of PGS.
PMID: 28449669 [PubMed - in process]
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Gleicher N, Metzger J, Croft G, Kushnir VA, Albertini DF, Barad DH Tags: Reprod Biol Endocrinol Source Type: research
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