Cholesterol Efflux Capacity, HDL Particle Number, and Incident Cardiovascular Events. An Analysis from the JUPITER Trial (Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin).

Conclusions -In JUPITER, cholesterol efflux capacity was associated with incident CVD in individuals on potent statin therapy but not at baseline. For both baseline and on-statin analyses, HDL particle number was the strongest of four HDL-related biomarkers as an inverse predictor of incident events and biomarker of residual risk. Clinical Trial Registration -URL: http://www.clinicaltrials.gov. Unique identifier: NCT00239681.
PMID: 28450350 [PubMed - as supplied by publisher]

Source: Circulation - April 27, 2017 Category: Cardiology Authors: Khera AV, Demler O, Adelman SJ, Collins HL, Glynn RJ, Ridker PM, Rader DJ, Mora S Tags: Circulation Source Type: research