Genetic diagnosis of familial hypercholesterolaemia: Preliminary data from the university of Padua outpatient lipid clinic

Background: Familial Hypercholesterolaemia (FH) is a common genetic cause of premature coronary heart disease (CHD) due to lifelong elevated plasma low-density lipoprotein (LDL) cholesterol levels. Aims of our study was to define the genotypic features of FH in relation to the clinical phenotype and the severity of the cardiovascular risk profile; assess the potential impact of genotypic characterization on response to drug therapy.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: Source Type: research