Regulation of inflammatory cytokines in human immunocompetent cells by propranolol in vitro

Conclusion: According to the results, propranolol inhibited the IL-13 and TNF-α expression in Jurkat and Molt-4 T- cells. The anti- inflammatory properties of propranolol may be partly due to its suppressive effect on inflammatory cytokines such as IL-13 and TNF-α. So propranolol along with its long-term usage in cardiovascular problems may be useful in treatment of inflammatory-based diseases such as COPD and allergic asthma.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 5.3 Allergy and Immunology Source Type: research