Two-year-old twin makes history after receiving hospital ’s 300th heart transplant

The cookies for Dean Andersen’s welcome-home celebration were decorated with “#300,” fitting for the two-year-old who, just six weeks earlier, received the 300th heart transplant performed at Boston Children’s Hospital. “Dean does things in his own time and in his own way,” says his mom, Janet Andersen. “His transplant was no exception.” The Boston Children’s Heart Transplant Program performed its first transplant in 1986, and this May marked the program’s 30th anniversary. Dean’s transplant in June was yet another reason for celebration. “Milestones like these are not accomplished without our amazing multidisciplinary staff, whose unending commitment and dedication provide an incredible model of excellence; the families and their children, who have taught us so much about resiliency, love, and true spirit; and lastly, the donor families, who in their worst hours of loss, could see through to the needs of another child and family to donate the gift of life,” says Dr. Elizabeth Blume, Heart Transplant Program medical director. A failing heart Dean was diagnosed with a congenital heart defect while Janet was still pregnant. When Dean was born, he was found to have a more complex, rare type of congenital heart disease, which included corrected transposition of the great arteries with pulmonary atresia and atrioventricular canal defect. This meant his heart was on the wrong side of his body, the ...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Our Patients’ Stories congenital heart defect Dr. Elizabeth Blume heart failure heart transplant Heart transplant program Pediatric Transplant Center (PTC) Pulmonary atresia Source Type: news

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Authors: Jastrzebska M, Marcinowska Z, Oledzki S, Chelstowski K, Siennicka A, Klysz M, Clark JS Abstract Antiplatelet therapy is considered as a standard procedure against atherosclerotic cardiovscular disease but this therapy has limited effect if resistance to acetylsalicylic acid or clopidogrel is present. Important factors associated with resistance are gender; or inflammation possibly associated with membrane microparticles (MP). It was decided to challenge the hypothesis that differential responses to dual antiplatelet therapy are conditioned by gender and/or proinflammatory status. The study involved 160 pat...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Publication date: 15 December 2018Source: New Scientist, Volume 240, Issue 3208Author(s):
Source: New Scientist - Category: Science Source Type: research
Publication date: Available online 15 December 2018Source: Reproductive BioMedicine OnlineAuthor(s): Georg Griesinger, Herman Tournaye, Nick Macklon, Felice Petraglia, Petra Arck, Christophe Blockeel, Peter van Amsterdam, Claire PexmanFieth, Bart CJM FauserThe pharmacological and physiological profiles of progestogens used for luteal phase support during assisted reproductive technology are likely to be important in guiding clinical choice towards the most appropriate treatment option. Various micronized progesterone formulations with differing pharmacological profiles have been investigated for several purposes. Dydrogest...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
ConclusionssLHCGR levels are negatively related to AMH when oocyte yield is high. High early cycle sLHCGR is associated with elevated day-3 oestradiol. Low sLHCGR and SOR are indicators of increased clinical pregnancy and live birth rates. Patient age and SOR, combined with EOR, might improve prediction of IVF treatment outcomes.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Publication date: Available online 16 December 2018Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Jun-Hui Wan, Jin Han, Yan-Dong Yang, Dong-Zhi Li
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Publication date: February 2019Source: Journal of Functional Foods, Volume 53Author(s): Yousi Fu, Junnan Zhang, Kainan Chen, Chuanxing Xiao, Lina Fan, Bangzhou Zhang, Jianlin Ren, Baishan FangAbstractThe current study investigated the effects of Dendrobium officinale polysaccharides (DOP) on human intestinal microbiota composition and metabolism via in vitro fermentation. Following 48 h of fermentation, 63.88% ± 2.40% of the total carbohydrate in the DOP was consumed and pH decreased from 6.95 to 4.70. Meanwhile, the total short chain fatty acid (SCFA) productions significantly increased, with the major SCFA b...
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Authors: Zeglinski MR, Moghadam AR, Ande SR, Sheikholeslami K, Mokarram P, Sepehri Z, Rokni H, Mohtaram NK, Poorebrahim M, Masoom A, Toback M, Sareen N, Saravanan S, Jassal DS, Hashemi M, Marzban H, Schaafsma D, Singal P, Wigle JT, Czubryt MP, Akbari M, Dixon IMC, Ghavami S, Gordon JW, Dhingra S Abstract Cardiovascular disease leading to heart failure (HF) remains a leading cause of morbidity and mortality worldwide. Improved pharmacological and interventional coronary procedures have led to improved outcomes following acute myocardial infarction. This success has translated into an unforeseen increased incidence i...
Source: Comprehensive Physiology - Category: Physiology Tags: Compr Physiol Source Type: research
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Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
ConclusionGRb1 is a potential natural GR agonist that protects against oxidative-stress-induced apoptosis of H9C2 cells.
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research
Time limit: 0 Quiz-summary 0 of 20 questions completed Questions: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Information This test series requires login for attempting. You can login easily with your Facebook account (Use the CONNECT WITH icon on the upper part of right sidebar displaying t...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs
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