Inspiratory muscle conditioning exercise and diaphragm gene therapy in Pompe disease: Clinical evidence of respiratory plasticity.

In conclusion, combined AAV1-CMV-GAA and exercise training conferred benefits to dynamic motor function of the diaphragm.Children with a higher baseline neuromuscular function may have greater potential for functional gains.
PMID: 27453480 [PubMed - as supplied by publisher]

Source: Experimental Neurology - July 20, 2016 Category: Neurology Authors: Smith BK, Martin AD, Lawson LA, Vernot V, Marcus J, Islam S, Shafi N, Corti M, Collins SW, Byrne BJ Tags: Exp Neurol Source Type: research