Cystatin C Predicts Incident Cardiovascular Disease in Twins [Vascular Medicine]

Conclusions
Variation in cystatin C relates to incident ASCVD and to stroke when adjusted for genetic confounding. In identical twins, cystatin C may be a sensitive marker of early hypertensive end-organ damage and small-vessel disease, whereas creatinine level may reflect nutritional status. The findings in disease-discordant monozygotic twins indicate that unique, possibly preventable, environmental factors are important.

Source: JAHA:Journal of the American Heart Association - June 26, 2016 Category: Cardiology Authors: Arpegard, J., Magnusson, P. K. E., Chen, X., Ridefelt, P., Pedersen, N. L., De Faire, U., Svensson, P. Tags: Nephrology and Kidney, Cardiovascular Disease, Cerebrovascular Disease/Stroke, Atherosclerosis, Coronary Artery Disease Vascular Medicine Source Type: research