Gambogic Acid Inhibits Malignant Melanoma Cell Proliferation Through Mitochondrial p66shc/ROS-p53/Bax-Mediated Apoptosis

Conclusion: Results provided novel preclinical insights into the chemotherapeutic use of GA by highlighting the importance of p66shc/ROS-p53/Bax pathways in the antitumor effect of GA in malignant melanoma.Cell Physiol Biochem 2016;38:1618-1630
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research