A Few Recent Omics Studies in Extremely Old Individuals

Below you'll find linked a few papers on the biochemistry of extremely old individuals, those who are in the portion of life in which they are heavily damaged by the processes of aging, most of their former peers are dead, and genetic variations become significant in determining quality of life and remaining life expectancy. A great deal of data is arriving on the biochemistry of the aged. The capacity of the research community to accumulate data on molecular biochemistry, in genetics, in epigenetics, and in the growing diversity of "omics" fields, of which genomics was only the first and least specialized, has for years greatly exceeded the capacity to analyze that data. Those fractions of the community concerned with making sense of it all will be playing catch-up for decades, I believe, given the pace of growth in data on the operation of human cellular metabolism - and given that productive and useful analysis is fundamentally a harder, more expensive, and more uncertain problem than collecting the data in first place. The ongoing revolution in biotechnology means that mountains of omics data are assembled today, and there is every sign that tomorrow's mountains will be an order of magnitude larger. So when you pick papers to read from the ongoing river of new studies that build upon human metabolic data, bear in mind that if the influx of new data stopped tomorrow, there would probably still be enough to productively occupy the research community for years yet. It is an...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs