A severe case of minocycline-induced DRESS resulting in liver transplantation and autoimmune sequelae

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a drug-induced hypersensitivity reaction that includes rash, hematologic abnormalities, lymphadenopathy, and internal organ involvement. The initial signs of fever, rash, and increased transaminase levels usually resolve once the acute episode subsides. However, physicians need to be aware that there are autoimmune sequelae that can develop long after the initial insult, such as thyroid dysfunction, lupus, and type 1 diabetes mellitus (T1DM).
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letter Source Type: research