Age-dependent blood pressure elevation is due to increased vascular smooth muscle tone mediated by G-protein signalling

Conclusion
Age-dependent blood pressure elevation is due to a highly reversible activation of procontractile signalling in vascular smooth muscle cells indicating that increased vascular tone can be a primary factor in the development of hypertension.

Source: Cardiovascular Research - December 28, 2015 Category: Cardiology Authors: Wirth, A., Wang, S., Takefuji, M., Tang, C., Althoff, T. F., Schweda, F., Wettschureck, N., Offermanns, S. Tags: Vascular Biology Source Type: research