Study: Manual thrombectomy increases stroke risk

Routine percutaneous coronary interventions with manual thrombectomies increase the risk of stroke compared to PCI alone, according to a new substudy published last month. The substudy, published online already and set to go to print in the European Heart Journal, examined a 10,058-patient cohort from the earlier Total study of PCI and manual thrombectomies to better understand the increase in stroke rate. The new analysis reported that the stroke difference was evident in as little as 48 hours, with 15 thrombectomy patients reporting an event versus 5 treated with only PCI. The overall risk was still low however, with a 0.3% risk associated with thrombectomy treatment and a 0.1% risk from PCI alone, according to the study. At 30-days, stroke rates in thrombectomy patients were more than double that of those treated with PCI alone, though the risks were again below 1% for both groups, with thrombectomy patients having a 0.7% risk and PCI only patients having a 0.3% risk. The difference in stroke rate continued to grow between 90 and 180 days. Stroke rates at 180 days were 1% for thrombectomy patients versus 0.5% for PCI-only patients. The rate of fatal strokes and strokes that led to major disabilities had double the rate in thrombectomy patients compared to PCI patients at 180 days, with 0.7% and 0.3% respectively. The study reported that both ischemic stroke and primary hemorrhagic strokes also occurred at higher rates in thrombectomy patients. There was no difference in ...
Source: Mass Device - Category: Medical Equipment Authors: Tags: Cardiovascular Catheters Clinical Trials European Heart Journal Source Type: news