Characterizing the presentation, management, and clinical outcomes of patients with intradural spinal chordomas: a systematic review

CONCLUSIONS: Treatment of intradural spinal chordomas primarily involves resection and radiotherapy. A significant challenge and complication in management is spinal tumor seeding after resection, with 9 studies proposing seeding as a mechanism of tumor metastasis in 11 cases. Factors such as tumor size, Ki-67 positivity, and distant metastasis may correlate with worse outcomes and demonstrate potential as prognostic indicators for intradural spinal chordomas. Further research is needed to improve understanding of this tumor and develop optimal treatment paradigms for these patients.PMID:38691865 | DOI:10.3171/2024.2.FOCUS2419

Source: Neurosurgical Focus - May 1, 2024 Category: Neurosurgery Authors: Max A Saint-Germain Patrick Kramer Carly Weber-Levine Kelly Jiang Abdel-Hameed Al-Mistarehi Kristin J Redmond Sang H Lee Chetan Bettegowda Nicholas Theodore Daniel Lubelski Source Type: research