The Effect of Thiazolidinediones in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

CONCLUSION: Both pioglitazone and rosiglitazone were associated with significant increases in body weight and BMI when compared with metformin or placebo. Pioglitazone significantly reduced triglycerides and fasting insulin when compared with placebo while rosiglitazone showed a modest reduction of LH when compared with metformin.PROSPERO REGISTRATION NO: CRD42020178783.PMID:38683294 | DOI:10.1007/s12325-024-02848-3

Source: Adv Data - April 29, 2024 Category: Epidemiology Authors: Mohammed A Abdalla Najeeb Shah Harshal Deshmukh Amirhossein Sahebkar Linda Östlundh Rami H Al-Rifai Stephen L Atkin Thozhukat Sathyapalan Source Type: research