Non-alcoholic fatty liver disease changes the expression and activity of hepatic drug-metabolizing enzymes and transporters in rats

In conclusion, NALFD changes the expression and activity of hepatic drug-metabolizing enzymes and transporters in rats, which may affect drug metabolism and pharmacokinetics. In clinical medication, drug monitoring should be strengthened to avoid potential risks.PMID:38663832 | DOI:10.1016/j.toxlet.2024.04.010

Source: Toxicology Letters - April 25, 2024 Category: Toxicology Authors: Yifei Shen Jie Liu Bingyi Yao Yuanjin Zhang Shengbo Huang Chenmeizi Liang Junze Huang Yu Tang Xin Wang Source Type: research