CircPDE5A-encoded novel regulator of the PI3K/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated de-ubiquitination of PIK3IP1
CONCLUSION: The novel protein PDE5A-500aa encoded by circPDE5A can act as an inhibitor of the PI3K/AKT signaling pathway to inhibit the progression of ESCC by promoting USP14-mediated de-ubiquitination of PIK3IP1 and may serve as a potential target for the development of therapeutic agents.PMID:38658954 | DOI:10.1186/s13046-024-03054-3
Source: Cell Research - Category: Cytology Authors: Kai Lei Ruihao Liang Jialu Liang Nan Lu Jing Huang Ke Xu Binghua Tan Kexi Wang Yicheng Liang Wenjian Wang Huayue Lin Minghui Wang Source Type: research
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