C/EBP β: A transcription factor associated with the irreversible progression of Alzheimer's disease

CONCLUSION: The overexpression of C/EBPβ accelerates the irreversible progression of AD pathophysiology. Additionally, C/EBPβ plays a crucial role in mediating multiple pathways linked to AD pathology, some of which engender vicious cycles, leading to the establishment of feedback mechanisms. To sum up, targeting C/EBPβ could hold promise as a therapeutic strategy not only for AD but also for other degenerative diseases.PMID:38644578 | PMC:PMC11033503 | DOI:10.1111/cns.14721
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Source Type: research