Mechano-sensor Piezo1 inhibits glucagon production in pancreatic α-cells

CONCLUSION: Our study uncovers the regulatory role of the Piezo1 ion channel in α cells. Piezo1 influences glucagon production by affecting mTOR signaling pathway.PMID:38653360 | DOI:10.1016/j.bbadis.2024.167185

Source: Biochimica et Biophysica Acta - April 23, 2024 Category: Biochemistry Authors: Wenying Guo Luyang Gao Haocong Mo Handan Deng Yawen Zhao Geyang Xu Source Type: research