Shared genetic aetiology of Alzheimer's disease and age-related macular degeneration by APOC1 and APOE genes
CONCLUSION: In this study, we confirmed the genetic pleiotropy between AD and AMD and identified APOC1 and APOE as pleiotropic genes. Further, the integration of multiomics data identified ZNF131, ADNP2 and HINFP as novel diagnostic biomarkers for AD and AMD.PMID:38646507 | PMC:PMC11029327 | DOI:10.1136/bmjno-2023-000570
Source: Herpes - Category: Infectious Diseases Authors: Xueli Zhang Zhuoting Zhu Yu Huang Xianwen Shang Terence J O'Brien Patrick Kwan Jason Ha Wei Wang Shunming Liu Xiayin Zhang Katerina Kiburg Yining Bao Jing Wang Honghua Yu Mingguang He Lei Zhang Source Type: research
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