PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt- β-catenin pathway

CONCLUSIONS: Our results demonstrate the PRMT6-YTHDF2-Wnt-β-Catenin axis promotes GBM migration, invasion, and EMT in vitro and in vivo, potentially serving as a therapeutic target for GBM.PMID:38637831 | DOI:10.1186/s13046-024-03038-3

Source: Cell Research - April 18, 2024 Category: Cytology Authors: Peng Yu Tutu Xu Wenmeng Ma Xiang Fang Yue Bao Chengran Xu Jinhai Huang Yongqing Sun Guangyu Li Source Type: research