Examining Differences in the Genetic and Functional Architecture of Attention-Deficit/Hyperactivity Disorder Diagnosed in Childhood and Adulthood

CONCLUSIONS: This study demonstrated that ADHD diagnosed later in life shows much stronger genetic overlap with internalizing disorders and related traits. This may indicate the potential clinical relevance of distinguishing these subgroups or increased misdiagnosis for those diagnosed later in life. Top transcriptome-wide SEM results implicated genes related to neuronal function and clinical characteristics (e.g., sleep).PMID:38633226 | PMC:PMC11021367 | DOI:10.1016/j.bpsgos.2024.100307

Source: Biol Sci Space - April 18, 2024 Category: Science Authors: Sophie Breunig Jeremy M Lawrence Isabelle F Foote Hannah J Gebhardt Erik G Willcutt Andrew D Grotzinger Source Type: research