Clinical prediction of opioid use disorder in chronic pain patients: a cohort-retrospective study with a pharmacogenetic approach

CONCLUSIONS: Functional polymorphisms related to OPRM1 variant and CYP2D6 phenotypes may predict a higher OUD risk. Established risk factors such as young age, elevated MEDD and lower incomes were identified. A predictive model is expected to be implemented in clinical setting among CNCP patients under long-term opioids use.PMID:38619184 | DOI:10.23736/S0375-9393.24.17864-9

Source: Minerva Anestesiologica - April 15, 2024 Category: Anesthesiology Authors: M ónica Escorial Javier Muriel Laura Agull ó Thomas Zandonai C ésar Margarit Domingo Morales Ana M Peir ó Source Type: research