High Levels of Serum Bile Acids in COVID-19 Patients on Hospital Admission

CONCLUSIONS: Severe or critical stage predominated, with serum bile acids and gamma-glutamyl transferase blood levels above normal ranges. The study suggests that serum bile acid is toxic at levels ≥10.1 µmol/L, and at such levels is involved in the inflammatory process and in progression to severe and critical clinical stages of the disease. In turn, this indicates the importance of monitoring bile acid homeostasis in hospitalized COVID-19 patients and including control of its toxicity in treatment protocols.PMID:36417335 | DOI:10.37757/mr2022.v24.n3-4.8

Source: MEDICC Review - November 23, 2022 Category: International Medicine & Public Health Authors: Felipe N Pi ñol-Jiménez Virginia Cap ó-de Paz Juli án F Ruiz-Torres Teresita Montero-Gonz ález Sara A Urgell és-Carreras Andr és Breto-García Armando Amador-Armenteros Mar ía M Llerena-Mesa Ana G Galarraga-Lazcano Source Type: research