Investigating the Spatial Distribution of Proliferating Cells in Primary Ovarian Cancers

CONCLUSIONS: Cell proliferation is a hallmark of OCs. This study provides new evidence that investigating the Ki67+ cell density and 2D distribution pattern can assist in understanding the proliferation status of OCs. Moreover, our computer models suggest that changes in Ki67+ cell density and their location are critical for maintaining the 2D distribution pattern.PMID:38531804 | DOI:10.24976/Discov.Med.202436182.60

Source: Discovery Medicine - March 26, 2024 Category: Research Authors: Mohamed A A A Hegazi Fabio Pasqualini Gianluigi Taverna Robert S Bresalier Maurizio Chiriva-Internati Fabio Grizzi Source Type: research