Assessment of multimodal treatment options in recurrent and persistent acromegaly: a systematic review and meta-analysis

ConclusionsThe management of persistent and recurrent acromegaly optimally requires a multimodal approach. In different scenarios of refractory acromegaly based on previous treatment, secondary treatments may vary in terms of remission rate and complications. Medical agents provide considerable effectiveness as a second-line therapy for recurrent or persistent disease. In selected cases, however, reoperation still provides an opportunity for cure or freedom from medications. The findings of this study may help clinicians to prioritize varying options involved in this multifaceted decision-making process.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research