High Blood Glucose, Triglycerides Linked to Long-Term Risk of Mental Disorders

Individuals with elevated blood levels of glucose and triglycerides have an increased risk of depression, anxiety, and stress-related disorders, as do individuals with low blood levels of HDL cholesterol ( “good cholesterol”), astudy inJAMA Network Open has found. Further, elevated levels of glucose or triglycerides were present in individuals who developed one of these disorders as far back as 20 years prior to diagnosis.Charilaos Chourpiliadis, M.D., of the Karolinska Institutet in Stockholm and colleagues analyzed data from 211,200 participants in the Apolipoprotein-Related Mortality Risk cohort who underwent occupational health screening between January 1, 1985, and December 31, 1996. As part of the screening, blood tests were done to measure glucose, total cholesterol, HDL cholesterol, LDL cholesterol ( “bad cholesterol”), triglycerides and other markers of metabolic and cardiovascular risk. The researchers determined clinical cutoffs for these blood markers based on previous research and/or cardiovascular disease guidelines.Study participants had a mean age of 42.1 years at their first screening and were followed for a mean of 21 years. The researchers examined the individuals ’ diagnoses in the Swedish Patient Register to look for a first diagnosis of depression, anxiety, or stress-related disorders. They defined stress-related disorders as acute stress reaction, posttraumatic stress disorder, adjustment disorders, other reactions to severe stress, and unspec...
Source: Psychiatr News - Category: Psychiatry Tags: anxiety blood test cardiovascular depression glucose good cholesterol HDL cholesterol Karolinska Institute stress triglycerides Source Type: research