A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.

Conditions: Gastroesophageal Junction Adenocarcinoma; Liver Cancer Stage IV; Biliary Tract Cancer; Pancreatic Adenocarcinoma; Colorectal Cancer; Gastric Cancer Interventions: Radiation: Hypofractionated radiotherapy/SBRT （5-8 Gy/fx，3-5 fx）; Drug: Anti-PD-1 monoclonal antibody; Drug: Oxaliplatin and Capecitabine; Drug: Anti-VEGF 15mg/kg; Drug: Anti-VEGF 7.5mg/kg; Drug: Gemcitabine and Cisplatin; Drug: Gemcitabine and Albumin paclitaxel Sponsors: Zhejiang Cancer Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials