Statins Do Not Significantly Affect Oxidative Nitrosative Stress Biomarkers in the PREVENT Randomized Clinical Trial

Conclusions: Atorvastatin demonstrated very modest effects on oxidative/nitrosative stress biomarkers in this low cardiovascular risk population. Our findings provide potential mechanistic insight into the lack of effect of atorvastatin on LVEF in the PREVENT trial.PMID:38573708 | DOI:10.1158/1078-0432.CCR-23-3952

Source: Clinical Cancer Research - April 4, 2024 Category: Cancer & Oncology Authors: Igor Makhlin Biniyam G Demissei Ralph D'Agostino W Greg Hundley Camelia Baleanu-Gogonea Nicholas S Wilcox Anna Chen Amanda M Smith Nathaniel Sean O'Connell James Januzzi Glenn J Lesser Marielle Scherrer-Crosbie Borja Ib áñez W H Wilson Tang Bonnie Ky Source Type: research