Deletion of Mixed Lineage Kinase Domain Like Pseudokinase Aggravates Chronic Alcohol-Induced Liver Injury via Increasing Apoptosis

ConclusionMLKL deletion did not prevent chronic alcohol-induced liver damage independently of necroptosis and exacerbated hepatic steatosis by increasing hepatocyte apoptosis.Graphical Abstract

http://link.springer.com/10.1007/s10620-024-08310-2

Source: Digestive Diseases and Sciences - March 29, 2024 Category: Gastroenterology Source Type: research