Systemic Connective Tissue Disease and Neuromyelitis Optica Spectrum Disorder Coexistence: A Systematic Review and Meta-Analysis

CONCLUSIONS: Our research found that the coexistence of these two disorders was more frequent in female rheumatologic patients with a SjS diagnosis with neurological manifestations and in neurologic patients for whom a SjS diagnosis was suspected. Similarly, NMOSD are less frequently found in SLE and very rarely incident in Mixed Connective Tissue Disease (MCTD) patients. These considerations should be taken into account in clinical experience of rheumatologists and neurologists, since early diagnosis of both conditions may influence the timing of immunosuppressive therapy and the prevention of systemic disabilities.PMID:38419451 | DOI:10.31083/j.jin2302035

Source: Journal of Integrative Neuroscience - February 29, 2024 Category: Neuroscience Authors: Jessica Elisabetta Esposito Giovanni Annoni Milena D'Amato Alessandra Graziosi Francesca Troilo Annalisa Di Risio Gilda Angelini Caterina Castiglione Pierluigi Tocco Paola Volpe Giancarlo Di Iorio Giustino Parruti Ennio Polilli Source Type: research