Esophageal squamous cell carcinoma transformed into neuroendocrine carcinoma after neoadjuvant immunochemotherapy: A case report

In conclusion, histological transformation to ENEC is a potential mechanism of acquired resistance to ICIs in ESCC. Prospective larger studies are warranted to further characterize ESCC-to-NEC transformation on use of ICIs.PMID:38476207 | PMC:PMC10928968 | DOI:10.3892/ol.2024.14317

Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Gaojie Xin Naicheng Song Ke Jiang Source Type: research